Imaging application NOTES
The FTIR600 stage is used to measure IR spectra at variable temperatures, and transformations between polymorphs followed in situ by heating and cooling the samples in the chamber.
Polymorphism in pharmaceutical solids has great implications on both the processing and the performance of solid pharmaceutical products. This app note details work from the School of Pharmacy at UCL using TASC with our DSC450 to characterise polymorphic transitions in the pharmaceutical active compound flufenamic acid .
TASC is a powerful technique to gain structural phase information, similar to DSC, from a range of our temperature control stages including the DSC450 and THMS600. This article discusses the advantages of this technique, with specific reference to its application in the analysis of polymer blends for drug delivery.
Rosario Esposito et al investigate the behaviour of melt inclusions up to 1360°C using the Linkam TS1400XY stage.