Market leader in temperature and environmental-controlled microscopy, Linkam, presented its range of cryo workflow solutions and sample characterisation tools at Microscopy and Microanalysis (M&M) 2022.
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New Development in Electron Microscopy Grid Vitrification
Linkam previewed its new cryo plunger—CryoGenium—an exciting new development in electron microscopy (EM) grid vitrification. Imaging of biological samples embedded in vitrified ice has become of great interest in recent years as it provides several advantages: the biological sample is in a fully hydrated state with superior preservation down to ultra structural level, a vitrified sample is naturally compatible with the vacuum required for EM/single particle (SPT)/correlative light and electron microscopy (CLEM), and cryo fluorescence provides very low photo-bleaching and high signal to noise imaging.
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Swansea Team Use Linkam Tool For PV Research
Researchers at Swansea University, UK, have shown it's possible to achieve near-unity charge generation quantum yields in organic solar cells. These findings present a route for designing and constructing higher-performance solar cells, which help to secure our future using renewable energy sources to meet sustainability goals.
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Linkam stage critical to solar cell research
Researchers at Swansea University, UK, have used a Linkam LTS420E-P stage to make temperature dependent measurements on organic photovoltaic cells.
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In the Press: Linkam Launches New Water Circulation Pump to Optimise Cooling of its Temperature Control Stages
Linkam Scientific Instruments, expert in sample characterisation, has launched a new Water Circulation Pump (WCP), designed specifically to provide optimised water cooling to its range of temperature and environmental control stages.
Liquid Crystal Sensor offers Breakthrough for Rapid COVID-19 Diagnostic Test
Researchers at OSU have designed a liquid crystal (LC) based diagnostic kit and a smartphone-based application to enable automatic detection of SARS-CoV-2 ssRNA, which could be used for reliable self-test of SARS-CoV-2 at home without the need for complex equipment or procedures. See how Linkam’s Peltier stage was in volved in the research.
In the press: Linkam Temperature-Controlled Stage Used in Research for Mars Missions
NASA’s Mars 2020 Perseverance rover will land on Mars on 18 February 2021, to search for signs of life and explore the planet's geology. The rover will explore the Jezero Crater to characterise the planet's ancient climate and geology, and will be the first mission to collect and cache Martian rock and regolith. The subsequent 2022 mission of the ExoMars programme will deliver a European rover and a Russian surface platform to the surface of Mars to search for signs of life.
In the press: Korea Polar Research Institute uses Linkam instrumentation
In the Press: Linkam Stages Used for Beamline Analysis
Linkam’s stages are being used by researchers at Diamond Light Source, the UK’s national synchrotron, for temperature and environmentally controlled beamline analysis experiments to support research in life, physical and environmental sciences.
In the Press: JA Woollam collaborates with Linkam on ellipsometry instruments
Linkam has modified the HFS600 heating stage with an optical adapter to facilitate use on an ellipsometer. This adapted temperature controller, now known as the HFSEL600, allows temperature-dependent ellipsometry measurements with all J. A. Woollam systems.
Researchers detect cancer cells at an early stage of development via luminescent nanothermometers
A recent study undertaken at Rovira i Virgili University in Tarragona, Spain, reveals that biolabelling through luminescence thermometry has the potential to detect cancer cells at an early stage of development, just by monitoring the temperature rise in the body, due to accelerated metabolic activities in abnormal cells.
The Linkam THMS600 stage was used by researchers at the university to study the fluorescence of the nanoparticles that are produced.
Preserving Historical Collagen-Based Artefacts and Paintings with the help of Linkam stages
In the Press: Diamond-Shaped Capillary Holder Insert Adds Flexibility to Linkam CAP500 Stage
Linkam Scientific Instruments has added a diamond-shaped capillary holder insert to its CAP500 stage, allowing the temperature control stage to be quickly and easily adapted to hold either of two capillary sizes simply by rotating the capillary holder.
In the Press: Cryo-Correlative Fluorescence and Electron Microscopy With Linkam’s CMS196V3 Stage
Cryo-imaging techniques are making the news across a wide range of applications. Cryo-imaging enables researchers to qualitatively assess the effectiveness of new compounds or biomolecules, and the CMS196V3 has been used by researchers from universities and research hospitals around the world to prepare and characterize many different sample types.
In the Press: Linkam THMS600 Stage Used to Study Laser-Induced Phase Separation
A team of scientists set out to understand how and why lasers trigger crystallization and how changes made to the properties of the laser could influence which crystal form would be generated. Researchers working with Prof. Klaas Wynne of The School of Chemistry at the University of Glasgow have used the Linkam THMS600 temperature-controlled stage to explore phase transitions in mixed liquid systems and laser-induced nucleation.
In the Press: Cryo-Correlative Fluorescence and Electron Microscopy With Linkam’s CMS196V³ Stage
The Linkam CMS196V³ is a cryo-CLEM instrument designed to facilitate the full workflow of CLEM. As well as maintaining the sample, it provides proven capabilities of safe handling of the sample, making it a simple and reliable process for transferring and imaging cryo samples with an optical microscope, while keeping them free of contamination at all times. With a short-start up time and an optional autofill system providing up to 6 hours of continuous, uninterrupted use, the CMS196V3 is time-efficient and increases workflow productivity. Furthermore, it enables co-ordinate mapping, required to locate the same sample in the fluorescence or Electron microscope.
Characterising Temperature-Dependent Drug-Polymer Miscibility Using Thermo-Microscopy
Investigating Intracellular Ice Formation with Cryomicroscopy
Advanced Mechanical Testing Technology for Understanding of Novel Nanomaterials
In the Press: Linkam Showcases New Liquid Cell for Its Modular Force Stage
Linkam Scientific Instruments showcased the latest version of its tensile stage. The company unveiled the new liquid cell module for the Modular Force Stage (MFS), which enables tensile testing of submersed samples in liquids up to 60°C.
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