Article

The importance of being small: miniaturisation of freeze drying equipment

Developmental activities for freeze-dried products are dictated by the limited availability and high cost of newly developed active compounds, and by Quality-by-Design requirements. Laboratory-scale freeze dryers used for formulation and process development show an excessive variety of designs and instrumentation concepts, making scale-up activities a challenge. The development of miniaturised equipment may provide enormous benefits in terms of development times and costs.

A Thermal Analysis Technique That Combines Differential Scanning Calorimetry and Light Microscopy

TASC is a powerful technique to gain structural phase information, similar to DSC, from a range of our temperature control stages including the DSC450 and THMS600. This article discusses the advantages of this technique, with specific reference to its application in the analysis of polymer blends for drug delivery.