Using the HFS600E-PB4 Linkam probe stage at tempertaures down to -70 °C (200K), this study looks at the temperature-dependent phase transitions affect the properties of piezoelectric materials, finding that ideal properties peaked around the low-temperature phase transitions.
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The author has made the full article available on their ResearchGate page here.
Researchers use the LTS420E-PB4 Linkam probe stage to analyse the carrier dynamics and optoelectronic properties of emerging near infrared (NIR) absorbing materials at temperatures as low as -190 °C.
Researchers use the Linkam CMS196 for imaging cryopreserved human prostate cancer cells with X-ray tomography. The CMS196 was used for cryo-fluorescence imaging of human PC3 prostate cancer cells, bringing insight into a new material used for a promising new non-invasive theraputive cancer treatment technique, Photo-Dynamic Therapy (PDT).
Full article available per CC BY 4.0.
Bolitho, E.M., Sanchez-Cano, C., Huang, H. et al. X-ray tomography of cryopreserved human prostate cancer cells: mitochondrial targeting by an organoiridium photosensitiser. J Biol Inorg Chem 25, 295–303 (2020). https://doi.org/10.1007/s00775-020-01761-8
Researchers use the Linkam CMS196 with correlative cryo-fluorescence and cryo-soft X-ray microscopy (cryo-CLXM) to observe endosomes and autophagosomes in mammalian cells.
Scientists at the London Research Institute of Cancer Research UK use the Linkam CMS196 for imaging mammalian cells with cryo-CLXM microscopy.
Researchers use the Linkam CMS196 as part of a Confocal Cryo Fluorescence Microscopy setup to image vitrified biological samples.
Schertel, Andreas, et al. "Imaging of Vitrified Biological Specimens by Confocal Cryo Fluorescence Microscopy and Cryo FIB/SEM Tomography." European Microscopy Congress 2016: Proceedings. Weinheim, Germany: Wiley‐VCH Verlag GmbH & Co. KGaA, 2016.
This study, using Linkam’s Freeze Drying system FDCS196, shows how the freeze-drying process can be used to preserve meat, discussing the effect of system pressure on the freeze drying efficiency.
Full Open Access article available via CC BY NC 4.0.
Prickett, Richelle C., et al. "Effect of supercooling and cell volume on intracellular ice formation." Cryobiology 70.2 (2015): 156-163.
Studying the effect of supercooling and cell volume on intracellular ice formation (IIF), using Linkam’s Freeze Drying system FDCS196.
Full article available per CC BY 4.0.
Prickett, Richelle C., et al. "Effect of supercooling and cell volume on intracellular ice formation." Cryobiology 70.2 (2015): 156-163.
Researchers use Linkam’s Freeze Drying system FDCS196 to cryopreserve red blood cells with slow cooling rates prior to storage at -80°C.
Full article available per CC BY 4.0.
Capicciotti, C.J. et al. Small Molecule Ice Recrystallization Inhibitors Enable Freezing of Human Red Blood Cells with Reduced Glycerol Concentrations. Sci. Rep. 5, 9692; DOI:10.1038/srep09692 (2015).
