Tensile properties of polycrystalline methane hydrate are analysed using the Linkam CAP500 under microscopy.
Full Open Access article available via CC BY 3.0.
Wan, Ye, et al. "An Experimental Study of the Formation of Talc through CaMg (CO3) 2–SiO2–H2O Interaction at 100–200 C and Vapor-Saturation Pressures." Geofluids 2017 (2017).
Cryogenic light microscopy is an important part a correlative imaging workflow, allowing confirmation of localised molecules of interest prior to processing for downstream analysis such ultrastructural or compositional assessment or in short: It is a key mapping step.
Here, the authors describe adaptation of a standard upright widefield microscope into a cryogenic 3D laser-free confocal system using the Linkam CMS196. We demonstrate the necessary sample preparation steps followed by confocal imaging of biological cells and tissues.
Access the full version here: https://analyticalscience.wiley.com/do/10.1002/was.00170086
Nizamudeen, Zubair Ahmed, et al. "Adaptive 3D cryogenic correlative light imaging of native biology using laser free confocal system. Wiley Analytical Science
Linkam provide sample characterisation solutions across a range of temperature and environmental control methods which can be used in combination with microscopic and spectroscopic analysis techniques. Here, we share our expertise in temperature-controlled microscopy with a discussion of how to assemble a dynamic data capture and imaging system.
Access the full version here: https://doi.org/10.1017/S1551929520001558
Stacey, D., & Gurney, R. (2020). An Image is Everything: A Tutorial on Choosing and Using the Components of a Dynamic Data Capture System. Microscopy Today, 28(6), 44-49. doi:10.1017/S1551929520001558
Researchers use Linkam’s BCS196 Cryobiology stage with optical microscopy to observe and measuree reactive uptake coefficients (γ ) of O3, NO3, and OH for several systems of oxidant and organic aerosol surrogate combinations.
Researchers use Linkam’s mechanical testing stage to investigate treatments for osteoporosis in fractures of femoral bones.
Full Open Access article availble via CC BY
Zimmermann, E., Schaible, E., Gludovatz, B. et al. Intrinsic mechanical behavior of femoral cortical bone in young, osteoporotic and bisphosphonate-treated individuals in low- and high energy fracture conditions. Sci Rep 6, 21072 (2016). https://doi.org/10.1038/srep21072
See how a unique setup using Linkam’s TS1500 allows researchers to perform beamline XRD analysis at high temperature at Diamond Light Source. Here, they use the new long-duration experimental beamline I11 to study phase formation kinetics of metal alloys, demonstrating a new technique for metallurgical studies.
Researchers used Linkam’s CSS450 to replicate the mechanical properties of natural silk by creating a synthetic polymer that solidifies when subject to flow. Using temperature-controlled shear in the aqueous phase they induce polymer crystallisation, providing an alternative low-energy polymer processing route.
Full Open Access article availble via CC BY 4.0
Dunderdale, Gary J., et al. "Flow-induced crystallisation of polymers from aqueous solution." Nature communications 11.1 (2020): 1-9.
Researchers used Linkam’s high TS1500 to quench silica glas from 1100°C, studying the resulting mechanical properties of the glass in order to undetsand the effects of heating, quenching and compression on the properties of glass.
Using Linkam’s high temperature stage TS1500, researchers look at the phase stability of nanocrystalline TiO₂ at temperatures up to 1000°C.
Using Linkam’s mechanical testing stage, a team of researchers at Imperial College London added geo-inspired double-walled nanotubes to a polymer matrix in order to improve the tensile properties.
Full Open Access article availble via CC BY
Inorganic Nanotube Mesophases Enable Strong Self-Healing Fibers Won Jun Lee, Erwan Paineau, David Benbow Anthony, Yulin Gao, Hannah Siobhan Leese, Stéphan Rouzière, Pascale Launois, and Milo Sebastian Peter Shaffer* ACS Nano 2020, 14, 5, 5570–5580 Publication Date:April 7, 202
Researchers study the effect of thermal excitation on semiconducting sensor materials using a Linkam probe stage, the HFS600E-PB4. They explore the temperature sensing performance of these semiconductor nanofilms.
Researchers use a Linkam probe stage, the HFS600E-PB4 to study the relationship between vertical interfaces and dielectric properties in thin nanocomposite films.
Researchers use Linkam’s Liquid Crystal System to study nematic liquid crystals for augmented reality displays.
Researchers use Linkam’s Liquid Crystal System to study nematic liquid crystals.
Researchers use Linkam’s Liquid Crystal System to study the chirality of liquid crystals.
Researchers use the Linkam CAP500 with fused silica capillaries to study the formation of talc, observing the process using techniques such as Raman spectroscopy and X-ray diffraction.
Full Open Access article available via CC BY 3.0.
Wan, Ye, et al. "An Experimental Study of the Formation of Talc through CaMg (CO3) 2–SiO2–H2O Interaction at 100–200 C and Vapor-Saturation Pressures." Geofluids 2017 (2017).
Researchers use the Linkam CAP500 to study the thermodynamic behaviour of CO2 capture systems, usingfused silica capillaries under Raman spectroscopy.
Researchers use the Linkam MFS to image and measure the tensile properties of nanocomposite samples synthesised by coagulation spinning using carbon nanotubes.
Researchers use the Linkam CMS196 for imaging cryopreserved human prostate cancer cells with X-ray tomography. The CMS196 was used for cryo-fluorescence imaging of human PC3 prostate cancer cells, bringing insight into a new material used for a promising new non-invasive theraputive cancer treatment technique, Photo-Dynamic Therapy (PDT).
Full article available per CC BY 4.0.
Bolitho, E.M., Sanchez-Cano, C., Huang, H. et al. X-ray tomography of cryopreserved human prostate cancer cells: mitochondrial targeting by an organoiridium photosensitiser. J Biol Inorg Chem 25, 295–303 (2020). https://doi.org/10.1007/s00775-020-01761-8
Researchers use the Linkam CMS196 with correlative cryo-fluorescence and cryo-soft X-ray microscopy (cryo-CLXM) to observe endosomes and autophagosomes in mammalian cells.
Scientists at the London Research Institute of Cancer Research UK use the Linkam CMS196 for imaging mammalian cells with cryo-CLXM microscopy.
